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The harm and disposal of blood oxygen saturation.
Jun 25, 2018

The harm and disposal of blood oxygen saturation. 

Hypoxia is an imbalance between oxygen supply and oxygen consumption, that is, tissue cell metabolism is in anaerobic state. Whether the body is anoxic depends on the oxygen volume and oxygen storage that the tissues receive to meet the need for aerobic metabolism. The damage of hypoxia was related to the degree of hypoxia, the rate of occurrence and duration.

Severe hypoxemia is a common cause of death in anesthesia, accounting for about 1/3 to 2/3 of deaths from sudden cardiac arrest or severe brain cell damage.

Clinically, the general pao2<80mmhg is low oxygen, which is basically equated with severe hypoxic blood disease. Hypoxia has a great effect on the organism. For example, the CNS, liver, kidney function of the influence. The first occurrence of hypoxia is compensatory heart rate acceleration, cardiac pacing and cardiac output increase, circulatory system with high dynamic state compensatory oxygen content deficiency. At the same time, blood flow redistribution, cerebral coronary blood vessels selective expansion to ensure adequate blood supply.

However, in severe hypoxia condition, because of endocardial lactic acid accumulation, ATP synthesis decreased, resulting in myocardial inhibition, resulting in bradycardia, anterior contraction, blood pressure drop and cardiac discharge volume decreased, as well as ventricular fibrillation and other arrhythmia and even stop. In addition, hypoxia and the patient's own disease may have a significant impact on the homeostasis of the patient's internal environment.

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